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 Technology Development Centre
Overview
Technology Development Centre (TDC) is our corporate Research & Development Centre for MSN group of companies. TDC is situated at Balanagar, heart of Greater Hyderabad City. The objective of the TDC is to develop new complex generic APIs using efficient, cost effective solutions on a very aggressive timeline.
All the key departments like R&D, AR&D, SCM and IPM are are under one roof to enhance the quality of products and deliver the product on time. Our New Product Development Team consists of more than 80 highly qualified scientists with proven track record. With over 7 ph.Ds and mostly masters graduates, our team consists top-notch process chemistry groups with excellent troubleshooting skills. Our team has extensive experience in working on complex molecules with multiple chiral centres.
Various Activities taken up at TDC are
New Product Development
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Identification of new product |
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Literature collection and review |
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Selection of non-infringing route |
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Design of experiments and execution |
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Novel polymorphs development and confirmations by powder XRD’s |
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Preparation of impurities and study |
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Chemical structures confirmations by using different spectroscopic studies like, NMR, Mass, Elemental analysis, UV, IR, DSC and TG Analytical Research & Development |
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Analytical methods developments for all the raw materials, intermediates and finished products |
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Preparations of analytical trend data’s and fixation of specifications |
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Cleaning method developments and validations |
Stability studies for intermediates and API's.
Chemistry Capabilities
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Asymmetric Synthesis |
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Reductions, Oxidations (Catalytic, Chemical) and Epoxidation |
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Negishi Coupling, Suzuki coupling |
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Julia Olefination, Wittig and Wittig-Horner reaction |
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Organo metallic (Grignard, Blaise, Reformatsky,etc) Reactions |
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Halogenation |
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Chlorosulphonation |
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PPA and PPE Reactions |
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Cryogenic Reactions (Up to -70° C) |
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Resolution & Racemisation |
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Alkylation & Amidation |
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Grignard Reactions |
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Cyanation Reactions |
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Rearrangement Reactions |
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Separation of multiple chiral compounds |
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High pressure, autoclave / hydrogenation reactions even at higher temperatures up to 250° C |
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Small scale (milligram) to bigger scale (2 kilos) can be handled in the laboratory |
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Dedicated pilot plant facility for further scale up |
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Equipped to handle reagents like n-butyl lithium, boron trifluoride, DIBAL, vitride, sodium azide, etc. |
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